Published: Wed, August 09, 2017
Science | By Boyd Webster

New Device Can Heal Organs In Less Than A Second

New Device Can Heal Organs In Less Than A Second

The Ohio State University researchers have developed a new device that they claim can heal organs with just a single touch. After a week, the new cells formed new blood vessels and nerve tissue. In less than a week, the technology generated blood vessels ultimately saving the leg.

In less than a second, this chip would deliver reprogramming factors (pre-programmed DNA or RNA) non-invasively into living skin cells via a high-intensity, focused electric field, converting them into whatever type of cells a scientist or doctor may choose. "We are proposing the use of skin as an agricultural land where you can essentially grow any cell of interest", he said.

While the ability to reprogram cells into being other cells is not new, this technology skips the old intermediary process that forces the skin cells to first become "pluripotent stem cells" before they can become functional cells for other organs.

The Guardian said that, according to researchers, this turns the patients' skin into a "bioreactor", allowing it to fix damaged tissue in the applied area or at another site on the body. These included using the device to act upon badly injured legs that lacked blood flow.

Thus far, researchers say that the technique has worked 98 percent of the time. "Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary", said Sen, who also is executive director of Ohio State's Comprehensive Wound Center. Through this process, the DNA will be converted to the specific building block cells of the damaged body part.

Dr Sen co-led the study with L. James Lee, professor of chemical and biomolecular engineering, Ohio State's College of Engineering in collaboration with Ohio State's Nanoscale Science and Engineering Center.

"What's even more exciting is that it not only works on the skin, but on any type of tissue", Sen said.

There would be no laboratory-based procedures ahead of use, meaning patients could just pick it up from a GP surgery when it is readily available. In my lab, we have ongoing research trying to understand the mechanism and do even better.

The technology could see cells grown on a human patient's skin and then injected into their body to treat conditions such as Parkinson's disease, Alzheimers, nerve damage and strokes.

Researchers plan to start clinical trials next year to test this technology in humans, Sen said.

Like this: