Published: Thu, August 24, 2017
Health Care | By Jeffery Armstrong

Could B Vitamin Megadoses Increase Actually Lung Cancer Risk For Male Smokers?

Could B Vitamin Megadoses Increase Actually Lung Cancer Risk For Male Smokers?

We observed no increased risk for any of the supplements - B6, B12, or folic acid - with lung cancer risk in women or women who smoked.

A new study suggests the body's stem cells can soak up unusually high levels of vitamin-C.

The researchers, from OSU and the National Taiwan University, found that those who took vitamin B supplements in recommended daily doses over a period of ten years faced 30 to 40 per cent higher risk of lung cancer.

This risk was further increased among male smokers who took more than 20 mg of B6 or 55 mg of B12 every day for ten years. While the findings are interesting, previous research could not find a definitive association between lung cancer and vitamin B supplements.

"This sets all of these other influencing factors as equal, so we are left with a less confounded effect of long-term B6 and B12 super-supplementation", Brasky said in a press release.

The researchers determined that men who now smoked and reported taking more than 20 milligrams (mg) of vitamin B6 daily during the 10-year period leading up to the study were about three times as likely to develop lung cancer than current smokers who didn't use B6 supplements at all.

Researchers at the James Cancer Hospital and Solove Research Institute said it is easy to get plenty of B vitamins from diet - foods like cereals are fortified with them, and some energy drinks have 8,000 percent of the recommended daily allowance of B12. And that's likely just because multivitamins generally don't contain high enough dosages of B6 and B12 to pose a risk.

For this study, Theodore Brasky, PhD, of the OSUCCC - James, and colleagues analyzed data from more than 77,000 patients participants in the VITamins And Lifestyle (VITAL) cohort study, a long-term prospective observational study created to evaluate vitamin and other mineral supplements in relation to cancer risk.

If you look at B-vitamin supplement bottles...they are anywhere between 50-fold the USA recommended dietary allowance (to) upward of 2,100-fold.

Researchers surveyed over 77,000 people ages 50 to 76 in Washington state.

Max Gomez reported, early studies seemed to show that they might, and they are now some of the most popular supplements sold in drug stores. This is the first study to prospectively examine the effects of extended, high-dose B6/B12 supplement use and lung cancer risk.

"As far as the magnitude of the association, I think you could characterize our reaction as concerned; especially if you consider how common these supplements are". Then, they followed up the participants for an average of about 6 years to see how many developed lung cancer. These supplements have been broadly thought to reduce cancer risk.

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